cheR [2017-8-11 16:0:3]

MCPs methyltransferase

locus: BSU22720

pI: 9.25

mw: 29.80 kDa

protein length: 256 aa

gene length: 768 bp

function: motility, chemotaxis

product: MCPs methyltransferase

essential: no

ec: 2.1.1.80

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.8|Protein modification/ other]
• [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.1|Signal transduction in motility and chemotaxis] → [category|SW 4.1.1.1.1|Soluble signalling proteins]

Gene

Coordinates: 2,380,347 → 2,381,117

The protein

Catalyzed reaction/ biological activity

• methylation of specific glutamate residues in the cytoplasmic domain of methyl-accepting chemotactic protein receptors (MCPRs)
• S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate methyl ester (according to Swiss-Prot)

Protein family

• Glu/Leu/Phe/Val dehydrogenases family (according to Swiss-Prot)

Structure

• [PDB|5FTW] (complex with S-adenosyl-L-homocysteine)

Expression and Regulation

Operons

• genes: [gene|1217807AE3AE3A654BA0DD4AF5ADF1CEE62632B6|cheR]-[gene|9712D0E655289C97315314BDEE1A0DF2ED2ADCA2|aroF]-[gene|58B782C1F7931F8671161455E65E3D5C72B0BB9C|aroB]-[gene|5C2F7F9F5FCBFEDF77AC41725EFDA0FAF0FC3BC1|aroH]
  description: [pubmed|22383849]

Biological materials

Mutant

• 1A830 ( ''cheR''::''cat''), [Pubmed|8244966], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A830&Search=1A830 BGSC]

References

Reviews

• 20122866

Original publications

• 8866475,21515776,25799883,27544050